[Date Prev][Date Next][Thread Prev][Thread Next][Date Index][Thread Index]

Re: [SANET-MG] a wierd attack on organic foods by biotech pr science



Hi Dale,


Dale Wilson wrote:

Joe,
I have not been able to find an accepted safety limit for methyl euginol in the literature or in FAO, IARC or FDA. As I pointed out earlier there was a clear consensus in the literature (I am enclosing quotes from two articles on metyl euginol risk below) all the peer reviwed articles indicate that the levels of methyl euginol that are found as spices in  foods are not high enough to significantly cause cancer.


The claims of methyl euginol  in food such as pesto at a level 600 times
the "accepted safety limit" are not found   in the peer reviewed
publications of science. The consensus is that  methyl euginol is
cancer causing in rodents but the levels of it found in flavoring are
too low to be of concern (see below). What I am pointing out  the
claims of the newspaper article seem to be exaggerated and not
consistent with  the consensus of food scientists. The
claims of the newspaper seem to be pure public relations. I think your
comments deal with something else?
sincerely, joe
Food Chem Toxicol. 2002,40:851-70
Safety assessment of allylalkoxybenzene derivatives used as flavouring
substances - methyl eugenol and estragole.
"In particular, rodent studies show that these events are minimal
probably in the dose range of 1-10 mg/kg body weight, which is
approximately 100-1000 times the anticipated human exposure to these
substances. For these reasons it is concluded that present exposure to
methyl eugenol and estragole resulting from consumption of food, mainly
spices and added as such, does not pose a significant cancer risk."

Toxicol Sci. 2002 Aug;68(2):275-9.
Thresholds of carcinogenicity of flavors.
"The three compounds with three doses fit a linear plot with a
correlation coefficient of at least 0.9; the four doses in male rats of
methyl eugenol fit a linear plot with a correlation coefficient of
0.999983. The intercept at zero percentage tumors of these linear fits
was at least several orders of magnitude greater than the estimated
daily dose of these flavoring agents to individuals in the United
States. This is interpreted to indicate that these flavoring agents have
a clear threshold for carcinogenicity in animals that is well above the
levels currently approved for use in foods; consequently, these animal
studies should not be a cause for concern for carcinogenicity of these
compounds in humans. Rather, the animal studies should be viewed as
providing evidence for the safety of these compounds at current levels
of human exposure."


A bitter row has broken out in Italy over the alleged toxicity of
one of the nation's favourite foods: pesto...
The problem ingredient is a carcinogenic agent called methyl-eugenol,
which is found to be present in the leaves of young basil plants...
According to Professor Francesco Sala of the Umberto Veronesi
Foundation, in a plate of spaghetti with pesto doc "there is a
concentration of methyl-eugenol 600 times higher than the accepted
safety limit...



Yes, a bizarre sort of argument to use to support transgenics.  The
basil argument does point out the absurdly conservative nature of
carcinogenic risk estimation methods applied to pesticides and food
additives.  Bruce Ames and Lois Gold wrote a helpful paper about this
several years ago.

http://www.fasebj.org/cgi/content/abstract/11/13/1041

Dale




__________________________________
Do you Yahoo!?
Check out the new Yahoo! Front Page.
www.yahoo.com

********************************************************
To unsubscribe from SANET-MG:
1- Visit http://lists.sare.org/archives/sanet-mg.html to unsubscribe or;
2- Send a message to <listserv@sare.org> from the address subscribed to the list. Type "unsubscribe sanet-mg" in the body of the message.

Visit the SANET-MG archives at: http://lists.sare.org/archives/sanet-mg.html
For more information on grants and other resources available through the SARE program, please visit http://www.sare.org.



********************************************************
To unsubscribe from SANET-MG:
1- Visit http://lists.sare.org/archives/sanet-mg.html to unsubscribe or;
2- Send a message to <listserv@sare.org> from the address subscribed to the list. Type "unsubscribe sanet-mg" in the body of the message.

Visit the SANET-MG archives at: http://lists.sare.org/archives/sanet-mg.html
For more information on grants and other resources available through the SARE program, please visit http://www.sare.org.