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[SANET-MG] toxic byproducts in gm potato



The GM potatoes involved in the study below are not the commercial Bt potatoes. However, the toxins in Bt potato need investigation!
J. Agric. Food Chem., ASAP Article 10.1021/jf050589r S0021-8561(05)00589-3
Web Release Date: September 2, 2005
Toxic Secondary Metabolite Production in Genetically Modified Potatoes in Response to Stress

Derek Matthews,* Huw Jones, Paul Gans, Steven Coates, and Lydia M. J. Smith
NIAB, Huntingdon Road, Cambridge CB3 0LE, United Kingdom, and Advanced Technologies (Cambridge) Ltd., Cambridge CB4 0WA, United Kingdom
Abstract:

Potatoes produce a number of toxic secondary metabolites, which are divided into two groups: the sesquiterpenes and the glycoalkaloids (PGAs): whereas PGAs are largely preformed and present in toxic quantities in both the foliage and "green" potatoes, it is well documented that the levels of PGAs and sesquiterpenes are effected by many biotic an abiotic stresses. The development of genetically modified potato varieties has made it prudent to ascertain whether there may be changes in the amounts or types of these secondary metabolites either as a direct effect of the transgene or due to its interactions with environmental variables. Transgenic potato lines were exposed, along with nontransgenic lines, to a range of biotic and abiotic stresses and a range of environmental conditions in the field and store. Following stressing, a comparison was made of levels of potato glycoalkaloid and sesquiterpene levels between the two groups. Significant differences were observed in the levels of both glycoalkaloid and sesquiterpene levels between transgenic and control material and between infected and noninfected material.

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