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Dissertation Information for Jamie Cuticchia

NAME:
- Jamie Cuticchia
- (Alias) Anthony James Cuticchia

DEGREE:
- Ph.D.

DISCIPLINE:
- Genetics

SCHOOL:
- University of Georgia (USA) (1992)

ADVISORS:
- None

COMMITTEE MEMBERS:
- None

MPACT Status: Incomplete - Not_Inspected

Title: Computational advances in the physical mapping of small eukaryotic genomes

Abstract: "Major efforts are underway to construct physical maps of whole genomes. Such techniques involve the use of restriction enzymes or short synthetic oligonucleotide probes. A third order Markov chain model can be applied to the accurate prediction of the frequencies of recognition sites for both of these molecular tools.

Binary data on clone collections assembled through hybridization experiments can be utilized to construct physical maps of chromosomes by the use of simulated annealing. This computational technique of combinatorial optimization has yielded extremely satisfactory results in the related the travelling salesman problem. Software has been developed to manage the data involved in binary mapping approaches as well as associating the data with the heuristics to produce the linear ordering of clones along a chromosome that comprises the physical map."

MPACT Scores for Jamie Cuticchia

A = 0
C = 1
A+C = 1
T = 0
G = 0
W = 0
TD = 0
TA = 0
calculated 2008-01-31 06:30:54

Advisors and Advisees Graph