Dissertation Information for Vladimir Arkadievich AzovNAME:
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SCHOOL: ADVISORS: COMMITTEE MEMBERS: MPACT Status: Fully Complete Title: I. Reactions within and between bilayer membranes. II. Synthesis and properties of water-soluble molecular asterisks Abstract: "Reactions between a nucleophile (hydroxamate) and an electrophile (an ester) were examined kinetically in solution and when one or both of the reagents were incorporated into vesicles (liposomes). Several modes of reactivity under comparable conditions have rates of decreasing magnitude according to intra-vesicular > solution/solution > solution/vesicle > inter-vesicular. The first and last categories of bond-forming reactions seem to have been investigated kinetically for the first time. Reactivity on a membrane surface depends markedly upon the affinity of the relevant functionalities for the aqueous medium. In the case at hand, one functionality (the hydroxamate) is fully exposed, whereas the other (the ester) is not, a situation that leads to a slow but observable vesicle/vesicle reaction. Vesicle/vesicle reactivity models numerous cell/cell reactions found in biology. |
MPACT Scores for Vladimir Arkadievich AzovA = 0 Advisors and Advisees Graph |