Frame.zip contains the program FRAME.EXE. This program is used to help identify open reading frames in DNA sequences. It does this based on codon usage and by the G+C content of the third base of the codon. This program is mainly geared for Streptomyces genes, but it should be useful for other high G+C content organisms. Different codon usage tables can be loaded to analyze genes from different organisms. Requirements: IBM compatible with VGA capable of 640x480 16 color. Source code is included. Gary Kleman Kleman@magnus.acs.ohio-state.edu