1 November 1990 LoopViewerÊis a Macintosh tool for drawing RNA secondary structures in molecular biology. LoopViewer accepts data in three forms: * CT (connect) file format, as produced by Micheal Zuker's MulFOLD programs and others. This CT format make contain multiple RNA molecules, in which case all molecules are drawn. * A string of sequences followed by a matching string of pairing characters. Each line contains only nucleotides or only pairings. * The format for Gary Olsen's LOOPSOL program. This is a sequence of nucleotides with base pairings interlaced among the nucleotides. In all cases, the text style of nucleotides, including color, size, font and text face will be copied into the secondary structure drawing. You may print a loop drawing, save it as a standard Macintosh PICTure file for further editing, or copy it to the clipboard. The current versions of LoopViewer and LoopDLoop will *not* run on Mac SE, Classic, LC or Mac Plus machines. They require Macintoshes with math coprocessors. Color is an option but not required. LoopViewer is a subset of a more complete RNA structure drawing and editing program, LoopDLoop. As of this writing, the complete LoopDLoop is still under development. LoopViewer may be used and distributed for free as long as its copyright notice is retained. It is available for anonymous ftp: ftp iubio.bio.indiana.edu user: anonymous cd [archive.molbio.mac] get loopviewer.hqx RNA secondary structures may be generated for input to LoopViewer with the MulFold program (available in this same ftp directory as mulfold.hqx). Don Gilbert Biocomputing Office, Biology Department Indiana University, Bloomington, IN 47405 Email: Don.Gilbert@IUBio.Bio.Indiana.Edu __________________________________________________________