From usenet.ucs.indiana.edu!sol.ctr.columbia.edu!zaphod.mps.ohio-state.edu!uakari.primate.wisc.edu!ames!bionet!ACHILLES.CTD.ANL.GOV!b44340 Thu Aug 20 16:20:39 EST 1992 Article: 494 of bionet.software Path: usenet.ucs.indiana.edu!sol.ctr.columbia.edu!zaphod.mps.ohio-state.edu!uakari.primate.wisc.edu!ames!bionet!ACHILLES.CTD.ANL.GOV!b44340 From: b44340@ACHILLES.CTD.ANL.GOV (A. Milosavljevic) Newsgroups: bionet.software Subject: server for identification of human repetitive DNA Message-ID: <9208201858.AA04421@achilles.ctd.anl.gov> Date: 20 Aug 92 18:58:53 GMT Sender: daemon@genbank.bio.net Distribution: bionet Lines: 47 Identification of Human Repetitive DNA Elements via Electronic Mail Aleksandar Milosavljevic Biological and Medical Research Division Argonne National Laboratory Argonne, Illinois 60439-4833 Jerzy Jurka Linus Pauling Institute of Science and Medicine 440 Page Mill Road Palo Alto California 94306 An electronic mail server at pythia@anl.gov has been installed that performs two kinds of tasks: (1) Identifies occurrences of around 50 known repetitive elements in human genomic DNA sequences. The regions that are identified as occurrences of repetitive elements in the incomming DNA sequence are aligned against the repetitive element. The alignments are then mailed back to the sender. (2) Identifies subfamily membership of Alu sequences The incoming sequence is first aligned against the Alu consensus sequence and then it is identified as belonging to one of the subfamilies of Alu sequences based on the bases in a set of diagnostic positions. To obtain more detailed information on the current availability of the services and on examples of its use, send a message with a word "help" in the "Subject"-line to the internet address pythia@anl.gov. The server is still in the testing phase, so please report any problems. We would also appreciate your comments on possible improvements of the server. Send your comments to pythia-admin@anl.gov. Work supported by the Grant DE-F603-91ER61152 from the U. S. Department of Energy, Human Genome Program, and in part by the U.S. Department of Energy, Office of Health and Environmental Research, under Contract No. W-31-109-ENG-38. The U. S. Government retains a nonexclusive, royalty-free license to publish or reproduce the published form of this contribution, or allow others to do so, for U. S. Government purposes.