SeqPup, version 0.4 development release, July 1995 SeqPup is a biological sequence editor and analysis program usable on the common computer systems including Macintosh, MS-Windows and X- Windows. It includes links to network services and external analysis programs. Features include multiple sequence alignment editor single sequence editor read and write several sequence file formats easy hand alignment features including colored bases and sliding automatic multiple sequence alignment thru ClustalW app automatic gel fragment alignment to contigs thru CAP app consensus, reverse, complement, degap operations restriction maps translate dna to/from protein using various codon tables find strings and ORFs automatic preference saving internet send mail internet sequence analysis services by email user-definable links to external analysis programs NOTICE: This release is still unfinish, and has bugs. Please careful of trusting important work to it. Yet it may be useful to some of you as is. SeqPup is being written by Don Gilbert using DCLAP, a free, portable C++ class application framework, and founded on the NCBI Toolkit, especially it's Vibrant user-interface section written primarily by Jonathan Kans. SeqApp/SeqPup was started in 1990 as sequence editor/analysis platform on which analysis programs from other authors could be easily incorporated into a useable interface. You can obtain this release thru anonymous ftp, gopher or http to iubio.bio.indiana.edu, in folder /molbio/seqpup. Versions are available for Macintosh, MS Windows, and these Unix/XWindows systems: Sun, SGI, DEC. The Internet locators to this software are Source code for this software is at . Comments, bug reports and suggestions for new features are very welcome and should be sent via e-mail to . July 95: Version 0.4 of SeqPup. This release includes most of the features of its parent, SeqApp, as well as new features and corrections. Alignment window: shift & slide sequences, copy/cut/paste/undo sequence entries among windows; Restriction maps and pretty print output; useable child apps for mac, mswin, and unix. It still contains bugs that cause the application to fail.