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A Workshop, presenting the basic concepts and applications of pharmacokinetics in the pharmaceutical, clinical, and veterinary sciences. For Whom Intended The Workshop is designed for pharmaceutical scientists, pharmacologists and other scientists, pharmacists, and physicians wishing to use pharmacokinetics in drug protocol design, in drug evaluation, in drug registration and in the establishment of dosage regimens. Emphasis is placed on relating pharmacokinetics to underlying physiological processes. Only limited exposure to pharmacokinetics is assumed. Workshop Content The Workshop is divided into lectures and small group workshops, in which participants will solve practical problems. A manual, comprising lecture outlines, derivations, problem sets with answers, and additional reading material will be provided. Participants should come with a scientific hand calculator. Topics to be covered include: 2. Clearance concepts in pharmacokinetics. 3. Assessment of pharmacokinetic parameters, from plasma and urine data, following intravenous bolus, constant rate infusion and extravascular (oral) administration. 4. Assessment of rate and extent of drug absorption; bioavailability. 5. Multiple dosing. 6. Integration of physiological concepts with pharmacokinetics. 7. Pharmacological response. 8. Distribution kinetics and mean residence time, introduction to assessment of parameters and consequences in pharmacokinetics.
Main Organiser MALCOLM ROWLAND Malcolm Rowland is Professor of Pharmacy, University of Manchester, England. He was both Assistant Professor (1967-1971) and Associate Professor (1971-1975) of Pharmacy and Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco. Professor Rowland received his B.Pharm. (1961), Ph.D. (1965) and D.Sc. (1978) from University of London. His main research interests are basic and theoretical aspects of pharmacokinetics and biopharmaceutics. He is the author of over 200 research articles, reviews and book chapters, and is an editor of the Journal of Pharmacokinetics and Biopharmaceutics. Together with Dr. T.N. Tozer, Professor Rowland has written Clinical Pharmacokinetics: Concepts and Applications 3rd ed, 1995. Faculty Leon Aarons School of Pharmacy, University of Manchester. Jeffrey K. Aronson MRC Clinical Pharmacology Unit, Radcliffe Infirmary, Oxford. Theodor W. Guentert F. Hoffman-La Roche Limited, Basel. School of Pharmacy, University of Basel Brian Houston School of Pharmacy, University of Manchester Stephen Toon Medeval, University of Manchester Geoffrey Tucker Dept. of Therapeutics, University of Sheffield.
Application Form Total fee, including board and lodgings, and service: UK£1150 sterling per person. The Workshop is limited to 70 applicants only. The Workshop will be in English. Ability to understand and converse in English is essential. A limited number of places, at a reduced fee, are available to academic persons. Further details are available upon request to Professor M. Rowland. If you would like an application form, please send your name and address to Ms Irene Sung at ISung@fs1.pa.man.ac.uk
Advanced Methods in Pharmacokinetics/ Pharmacodynamics Workshop For those who have a good working knowledge of basic concepts in pharmacokinetics, pharmacodynamics and data analysis, and who wish to extend their technical knowledge further, a similar 4.5 day workshop on advanced approaches will be offered by Professors Rowland and Sheiner, 22-26 March 1998 (Sils-Maria, Switzerland). For information, please contact Ms Irene Sung, School of Pharmacy, University of Manchester, Manchester M13 9PL, England.
LOCATION OF WORKSHOP Manchester Business School, University of Manchester, Booth Street West, Manchester M15 6PB ACCOMMODATION Accommodation will be available through the nights of 5th to 9th July 1998 at the Manchester Business School. The cost of accommodation is included in the Workshop. ALL MEALS All meals are included in the cost of the Workshop. PUBLIC TRANSPORT Manchester is reached readily by rail and by air. There is a frequent bus service to the Manchester Business School from Piccadilly and Victoria Bus Stations. Alternatively, the short journey (1-2 miles) from either Piccadilly or Victoria Train Stations can be made by taxi. A train to Piccadilly Station or a taxi is available from Manchester Airport. FEE Total fee, including board and lodgings, UK£1150 per person. Cancellation of a place will incur a charge of UK£100. Late cancellation may result in no refund. FURTHER ENQUIRIES
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