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Symposia

Tuesday, 2 September

09.00-12.00

S1 Advances in Drug Delivery

Chairs: Tsuneji Nagai, Japan and Daan Crommelin, The Netherlands
(In honour of Prof. W.I. Higuchi for his lifetime achievements)

a Biophysical! Model approach to drug delivery Norman Ho, USA

b A novel method based on artificial neural networks for optimising transdermal drug delivery systems Kozo Takayama, and Tsuneji Nagai, Japan

c Prodrug approaches for optimisation of drug delivery Brad Anderson, USA

d Unravelling the complexities of the oral absorption process: Predicting human drug absorption Gordon Amidon, USA

09.00-12.00

S2 Advances in Bioanalytical Procedures: New Instruments and New Techniques

Chairs: Toshio Nambara, Japan and Gordon McKay, Canada
(In honour of Prof. R.T. Coutts for his lifetime achievements)

a A unique edman sequencing method for peptides/proteins containing d-amino acids Kazuhiro Imai, Japan

b Enantiomeric resolution of drugs by capillary electrophoresis Jacques Crommen, Belgium

c Modern spectroscopic techniques in biodiagnostics Ian Smith, Canada

d Highly specific and sensitive analytical procedures for drugs and their metabolites: RIA to tandem mass spectrometry Gordon McKay, Canada

09.00-12.00

S3 Receptor Research Towards Drug Design and Treatment

Chairs: Douwe Breimer, The Netherlands and Kamal Midha, Canada
(In honour of Prof. E. Mutschler for his lifetime achievements)

a Selective P2-receptor antagonists: Design, pharmacology and therapeutic potential Gnter Lambrechts, Germany

b Research towards drug design and treatment Pieter Timmermans, USA

c Dopamine receptors and antipsychotic drugs: Basics and clinical Philip Seeman, Canada

d Molecular mechanisms governing the selectivity of receptor/g protein interactions Jrgen Wess, USA

09.00-12.00

P1 Developing Optimal Working Relationships with Physicians

Chairs: Leo-Paul Landry, Canada and Almar Grimsson, Iceland
Sponsored by an educational grant from Amgen Inc.)

a The impact of the role of the pharmacist on the physician George Carruthers, Canada

b Benefits of co-operation between doctors and pharmacists Dick Tromp, The Netherlands

c Future developments: Collaboration or competition? Albert Wertheimer, USA

Panel discussion

12.15-13.00

Update lecture: 1

Impact of cytochrome metabolism in drug safety and efficacy Geoffrey Tucker, UK

14.00-17.00

S4 New Drug Development: New Strategies

Chairs: Vincent Lee, USA and Elisabeth Vadas, Canada
(Sponsored in part by an educational grant from Sandoz Canada Inc.)

a Drug discovery George Poste, UK

b Drug absorption assessment William Curatolo, USA

c Drug metabolism assessment Yuichi Sugiyama, Japan

d Drug pre-formulation and formulation Colin Gardner, USA

14.00-17.00

S5 Advances in Scientific Regulations of Medicine

Chairs: Ian McGilveray, Canada and Ryoji Konishi, Japan
(Sponsored by an educational grant from Hoechst Marion Roussel)

a Recent advances in pharmaceutical regulation in Japan: Industrial scope Ryoji Konishi, Japan

b Biologicals and biotech substances: advances in public standards development in Europe Jean-Marc Spieser, France

c Use of in-vitro metabolism to predict safety and efficacy problems in developing market application (US) David Greenblatt, USA

d Advances in scientific regulation of medicine Roger Williams, USA

14.00-17.00

P2 Improving the Care of the Diabetic Patient

Chairs: Hermann Ammon, Germany and Maryann Hopkins, Canada
(Sponsored by an educational grant from Bayer Inc. Canada)

a Issues and challenges in diabetic care Hermann Ammon, Germany

b The role of the pharmacist - A US model Condit Steil, USA

c From guidelines to outcomes for diabetic care Maria Augusta Soares, Portugal

d Diabetes mellitus: New biological markers of long term complications and management of the care of diabetic patients Franois Trivin, France

Panel discussion

14.00-17.00

P3 Responding to Changes in Health Care Systems

Chairs: William Zellmer, USA and Yves Garipy, Canada
(In honour of Dr. J. Oddis for his liftime achievements)
(Sponsored by an educational grant from Glaxo Wellcome Canada Inc.)

a Developments in the public-private financing of health care Robert Evans, Canada

b Comparing international trends in health care reform Peter Bogaert, Belgium

c Health care reform a threat or opportunity for pharmacy? Pierre Sado, France

Panel discussion

Wednesday, 3 September

09.00-12.00

S6 Diabetes Therapy - Current Status

Chairs: Bernard Zinman, Canada and Pierre Lefebvre, Belgium

a Physiologic insulin replacement - An elusive goal Bernard Zinman, Canada

b Current management of type II diabetes mellitus Pierre Lefebvre, Belgium

c Insulin treatment from the viewpoint of controlled release and targeting Ryuzo Kawamori, Japan

d Type I diabetes: A reality or a pipe dream? Francine Kaufman, USA

09.00-12.00

S7 Gender Issues

Chairs: Mary Berg, USA and Donna Stewart, Canada
(Sponsored by an educational grant from Eli Lilly Canada Inc.)

a European studies in women’s health Hildgegard Sourgens, Germany

b Gender framework of health research Mary Berg, USA

c Speaker and topic to be announced

d Speaker and topic to be announced

09.00-12.00

P4 Measuring Outcomes of Pharmacy Practice

Chairs: Christopher Kozma, USA and Hanne Herborg, Denmark

a Do we improve patient outcomes? Christopher Kozma, USA

b Are pharmacists value for money? Bert Leufkens, The Netherlands

c Quality of life and patient satisfaction: Outcomes of pharmacy practice Linda MacKeigan, Canada

Panel discussion

12.15-13.00

Update lecture: 2

Taxol and other advances in cancer treatment Karen Gelmon, Canada
(Sponsored by an educational grant from Bristol-Myers Squibb, Canada Inc.)

14.00-17.00

S8 Pharmacoeconomics

Chairs: Jim Blackburn, Canada andAbraham Hartzema, USA
(Sponsored by an educational grant from Glaxo Wellcome Plc.)

a Applying the modelling approach to pharmacoeconomics Brian Rittenhouse, Canada

b A European experience from the manufacturer’s perspective Jeremy Chancellor, UK

c Evaluation of the pharmaceutical assessment programme at the Canadian Co-ordinating Office for Health Technology Assessment: Protocols, Studies and Products Nicolaas Otten, Canada

d Pharmacoeconomic evaluation - A governmental perspective Andrew Mitchell, Australia

14.00-17.00

P5 Protocols and Guidelines for Pharmaceutical Care:

New Challenges for Pharmacists

Chairs: Linda Stone, UK and Jim Blackburn, Canada
(Sponsored in part by an educational grant from Sandoz Canada Inc.)

a Integrating pharmaceutical care, managed care and disease management Lucinda Maine, USA

b Protocol development in primary care Speaker to be announced

c Implementing protocols in primary care Terry Maguire, Northern Ireland

Panel discussion

Thursday, 4 September

09.00-12.00

P6 Self-Medication - The Trend of the Future

Chairs: Peter Noyce, UK and Barbara Wells, Canada
(Sponsored by an educational grant of Whitehall Robins Inc.)

a Distribution of non-prescription medicines in the information economy David Skinner, Canada

b A patient perspective on self-medication and self-care Maj-Britt Hedvall, Finland

c Advising the self-medicating patient Peter Noyce, UK

d Can we measure the impact of the pharmacist’s role with respect to self-medication? Speaker to be announced

12.15-13.00

Update lecture: 3

Genes for inherited defects in children and treatment Linda Surh, Canada

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