Vol. 18, No. 17, May 12, 1989 NOTICES NOTICE OF MEETING - OPEN MEETING ON CONFLICTS OF INTEREST ......(84/157)..... 1 National Institutes of Health Alcohol, Drug Abuse, and Mental Health Administration Index: NATIONAL INSTITUTES OF HEALTH ALCOHOL, DRUG ABUSE, MENTAL HEALTH DIRECTORY OF INTERNATIONAL GRANTS AND FELLOWSHIPS IN THE HEALTH SCIENCES .......................................................(161/183).... 2 Fogarty International Center Index: FOGARTY INTERNATIONAL CENTER DATED ANNOUNCEMENTS (RFPs AND RFAs) ADDENDUM: AVOIDABLE MORTALITY FROM CANCER IN NATIVE AMERICAN POPULATIONS (RFA) ..............................................(189/233).... 2 National Cancer Institute Index: CANCER ADDENDUM: PRIMARY PREVENTION: SMOKING/SMOKELESS TOBACCO USE AND DIETARY CHANGE IN NATIVE AMERICAN POPULATIONS (RFA) ............(241/287).... 3 National Cancer Institute Index: CANCER COOPERATIVE AGREEMENT FOR METHODOLOGIC RESEARCH FOR MULTI-SITE EPIDEMIOLOGIC SURVEYS OF MENTAL DISORDERS IN CHILD AND ADOLESCENT POPULATIONS (RFA) ...................................(290/342).... 3 National Institute of Mental Health Index: MENTAL HEALTH ONGOING PROGRAM ANNOUNCEMENTS SPECIAL EMPHASIS RESEARCH CAREER AWARD (SERCA) IN OCCUPATIONAL SAFETY AND HEALTH ..............................................(348/494)... 4 Centers for Disease Control National Institute for Occupational Safety and Health Index: CENTERS FOR DISEASE CONTROL NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH MINORITY INSTITUTIONS RESEARCH DEVELOPMENT PROGRAM .............(497/568).... 6 National Institute of Mental Health National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse Index: MENTAL HEALTH, ALCOHOL ABUSE, ALCOHOLISM, DRUG ABUSE ENVIRONMENTAL HEALTH SCIENCES CORE CENTER GRANTS ...............(571/603).... 7 National Institute of Environmental Health Sciences Index: ENVIRONMENTAL HEALTH SCIENCES NOTICES NOTICE OF MEETING - OPEN MEETING ON CONFLICTS OF INTEREST P.T. 42; K.W. 1014004, 1014006 National Institutes of Health Alcohol, Drug Abuse, and Mental Health Administration On June 27 and 28, 1989, the National Institutes of Health and the Alcohol, Drug Abuse, and Mental Health Administration (NIH/ADAMHA) will sponsor an open meeting at the Masur Auditorium of the Warren G. Magnuson Clinical Center at NIH in anticipation of guidelines to govern standards of conduct about potential or apparent conflicts of interest for grantee and contractor institutions/organizations and individuals. The goal of the meeting is to create a framework within which institutions/organizations could develop approaches to oversight of their conflict of interest situations. In addition, it is critical to clarify appropriate standards for research projects spanning the breadth of the science NIH/ADAMHA supports. While guidelines must be flexible enough to allow for institutional/organizational governance, NIH/ADAMHA is seeking to articulate a standard which all institutions must meet to be eligible for funds. All interested parties are encouraged to attend. We invite broad attendance. Pre-registration is required due to the limited capacity of the auditorium. If you plan to attend, please send a fee of $10 for coffee breaks and miscellaneous expenses together with you name, affiliation, address, and phone number to: Mark S. Brown Social and Scientific Systems, Inc. 7101 Wisconsin Avenue, Suite 610 Bethesda, Maryland 20814-4805 Telephone: (301) 986-4870 The check should be made out to Social and Scientific Systems, Inc. Any questions may be directed to the above contact. The meeting will define conflicts of interest from judicial, congressional, industrial, and academic perspectives. It will address the opportunities and problems that occur when an academic/non-profit institution develops for-profit subsidiaries while receiving government research funds. Discussion will also address issues that directly involve the scientist such as: (1) Is it possible that funds, stock ownership, equipment, etc. from for-profit organizations will unduly influence research results? (2) How should outside activities such as honoraria, consultantships, etc. be treated when an investigator has a Federal grant or contracts for work related to the aims of that outside organization? (3) What should be the accepted policy for disposition of intellectual and biological property obtained from government-financed research? Who should finance retention and sharing? and, (4) Are students or research plans being directed to areas of lesser scientific or scholarly merit to enhance the potential for monetary gains? Issues that relate to institutional responsibility include determination of the responsibility, nature, and appropriate focus for oversight. What should be the guiding principles for evaluating assurances and waivers? What remedies and/or sanctions, if any, should be instituted? Interested parties from all sectors may send written comments by June 15 to: Dr. Katherine L. Bick Deputy Director for Extramural Research National Institutes of Health Shannon Building, Room 144 Bethesda, Maryland 20892 Although written comment is strongly encouraged, opportunity will also be available for participants to speak during the discussions at the meeting. Following this meeting, NIH/ADAMHA intends to develop appropriate guidelines that will clarify pertinent types of research situations and personal financial interests consistent with the PHS Grants Policy Statement, January 1, 1987, revision, concerning Standards of Conduct for Employees for awardee organizations, and to define appropriate distributions or governance between NIH/ADAMHA and awardee organizations. This open meeting is designed to elicit comments from concerned and interested individuals and institutions prior to development of general guidelines. Vol. 18, No. 17, May 12, 1989 - Page 1 DIRECTORY OF INTERNATIONAL GRANTS AND FELLOWSHIPS IN THE HEALTH SCIENCES P.T. 16, 22, 34; K.W. 0710030, 0720005 Fogarty International Center The Fogarty International Center (FIC), National Institutes of Health (NIH), announces the availability of a limited number of booklets entitled Directory of International Grants and Fellowships in the Health Sciences. This is an updated and expanded version of the Directory of International Opportunities in Biomedical and Behavioral Sciences that was published in February 1988. To receive a copy of this booklet, please enclose a self-addressed label with your request to: International Research and Awards Branch Building 38A, Room 613 Fogarty International Center National Institutes of Health Bethesda, Maryland 20892 Because of the anticipated response, only those requests that are accompanied by a self-addressed label will receive a response. DATED ANNOUNCEMENTS (RFPs AND RFAs) ADDENDUM: AVOIDABLE MORTALITY FROM CANCER IN NATIVE AMERICAN POPULATIONS RFA: 89-CA-10 P.T. 34, FE; K.W. 0715035, 0745027, 0404000 National Cancer Institute Application Receipt Date: August 3, 1989 This Request for Applications (RFA) was announced in the Vol. 18, No. 10, March 24, 1989 issue of the NIH Guide for Grants and Contracts. The full RFA that was distributed in response to that announcement requires further clarification of two statements. Refer to the full RFA when reviewing the following clarifications: o V. RESEARCH OBJECTIVES AND SCOPE -- Overview, Lines 1-8 (page 5 of the full RFA): This study of Avoidable Mortality of Cancers in Native Americans is envisioned as taking place in four or five different U.S. geographic regions. (The ideal set of awards would include representatives from Alaska, Hawaii, and several regional areas in the contiguous [or "lower 48"] states.) The ideal set of awards will allow the assessment of cancer control and prevention intervention strategies in the Native Hawaiian population as well as Alaskan Natives and American Indians from different linguistic (migratory origin) groups. o XI. REVIEW PROCEDURES AND CRITERIA -- REVIEW CRITERIA, Item 3, line 5 (page 14 of the full RFA): o experience of the investigators and other key personnel in the conduct of cancer prevention and control intervention or other health-related intervention studies. If you should have additional questions or require additional information, please contact: Gregory M. Christenson, Ph.D. Special Populations Studies Branch Division of Cancer Prevention and Control National Cancer Institute Executive Plaza North, Room 240 9000 Rockville Pike Bethesda, Maryland 20892 Telephone: (301) 496-8589 Vol. 18, No. 17, May 12, 1989 - Page 2 ADDENDUM: PRIMARY PREVENTION: SMOKING/SMOKELESS TOBACCO USE AND DIETARY CHANGE IN NATIVE AMERICAN POPULATIONS RFA: 89-CA-11 P.T. 34, FE; K.W. 0715035, 0745027, 0404019, 0404000 National Cancer Institute Application Receipt Date: August 3, 1989 This Request for Applications (RFA) was announced in the Vol. 18, No. 10, March 24, 1989 issue of the NIH Guide for Grants and Contracts. The full RFA that was distributed in response to that announcement requires further clarification of two statements. Refer to the full RFA when reviewing the following clarifications: o V. RESEARCH OBJECTIVES AND SCOPE -- Overview, lines 1-7 (page 5 of the full This study of Primary Prevention in Native Americans is envisioned as taking place in different U.S. geographic regions. (The ideal set of awards would include representatives from Alaska, Hawaii, and several regional areas in the contiguous [or "lower 48"] states.) The ideal set of awards will allow the assessment of intervention strategies in the Native Hawaiian population as well as Alaskan Natives and American Indians from different linguistic (migratory origin) groups. o XI. REVIEW PROCEDURES AND CRITERIA -- REVIEW CRITERIA, Item 3, line 5 (page 14 of the full RFA): o experience of the investigators and other key personnel in the conduct of cancer prevention and control intervention or other health-related intervention studies. If you should have additional questions or require additional information, please contact: Gregory M. Christenson, Ph.D. Special Populations Studies Branch Division of Cancer Prevention and Control National Cancer Institute Executive Plaza North, Room 240 9000 Rockville Pike Bethesda, Maryland 20892 Telephone: (301) 496-8589 COOPERATIVE AGREEMENT FOR METHODOLOGIC RESEARCH FOR MULTI-SITE EPIDEMIOLOGIC SURVEYS OF MENTAL DISORDERS IN CHILD AND ADOLESCENT POPULATIONS RFA AVAILABLE: MH-89-22 P.T. 34, AA; K.W. 0785055, 0715129, 0404021 National Institute of Mental Health Application Receipt Date: July 12, 1989 The National Institute of Mental Health (NIMH) is requesting applications for the first phase of an epidemiologic survey program of mental disorders of U.S. children and adolescents, ages 9-17. Phase I is to plan and conduct methodologic research to evaluate survey instruments and to develop procedures which could be used in Phase II. Phase II is a full-scale, multi-site epidemiologic and services research study. The program will be carried out as a cooperative agreement to allow for collaborative activity among the sites and NIMH. Applications may be submitted by any domestic public or private nonprofit or profit-making organization such as universities, colleges, hospitals, units of State or local government, and authorized units of the Federal Government. Applicants may request Phase-I support for 3 years. It is anticipated that up to $3 million will be available to support up to six new cooperative agreement awards under this announcement during fiscal year 1989; funding in future years will depend on annual appropriations. Applications must be submitted by July 12, 1989. Vol. 18, No. 17, May 12, 1989 - Page 3 Potential applicants wishing further information should contact: Child and Youth Epidemiology Ben Z. Locke, M.S.P.H. Chief, Epidemiology and Psychopathology Research Branch Division of Clinical Research Room 10C-05 Telephone: (301) 443-3774 Services Utilization Jack D. Burke, M.D., M.P.H. Director, Division of Biometry and Applied Sciences Room 18C-26 Telephone: (301) 443-3683 The mailing address for both of the above is: National Institute of Mental Health 5600 Fishers Lane Rockville, Maryland 20857 ONGOING PROGRAM ANNOUNCEMENTS SPECIAL EMPHASIS RESEARCH CAREER AWARD (SERCA) IN OCCUPATIONAL SAFETY AND HEALTH P.T. 34; K.W. 0725020, 0710030 Centers for Disease Control National Institute for Occupational Safety and Health Application Receipt Dates: March 1, July 1, November 1 BACKGROUND AND OBJECTIVES This announcement is a modification to the existing provisions and eligibility requirements for National Institute for Occupational Safety and Health (NIOSH) SERCA grants. Its purpose is to define more precisely the type of research to be supported, eliminate the two-year post-doctoral research experience requirement, establish a three-year award period only, and increase the annual direct costs support level to $50,000. The NIOSH SERCA grant is intended to: (1) provide opportunities for individuals with developing research interests to acquire experience and skill essential to the study of work-related hazards; (2) provide support for individuals to pursue a program of research in various disciplines; and (3) create a pool of highly-qualified investigators with experience and skills in the area of occupational safety and health. NIOSH SERCA grants are not intended either for individuals without research experience or for productive, independent investigators with a significant number of publications and of senior academic rank. Moreover, the award is not intended to substitute one source of salary support for another for an individual who is already conducting full-time research; nor is it intended to be a mechanism for providing institutional support. ELIGIBLE APPLICANTS Candidates for a SERCA must: (1) hold a doctoral degree; (2) have research experience at least at the doctoral level; (3) not be above the rank of associate professor; and (4) be citizens or noncitizen nationals of the U.S. or its possessions or territories or must have been lawfully admitted to the U.S. for permanent residence at the time of application. Eligible applicants may reside at non-profit or for-profit organizations such as universities, colleges, research institutions, and other public and private organizations including State and local governments and small, minority, and/or woman-owned businesses. PROGRAM REQUIREMENTS This non-renewable award provides support for a three-year period for individuals engaged in fulltime research and related activities, and may comprise direct costs of up to $50,000 per year and additional indirect costs of 8 percent. Related activities may include research career development Vol. 18, No. 17, May 12, 1989 - Page 4 activities, as well as involvement in patient care to the extent that it will strengthen research skills. Fundamental/basic research will not be supported unless the project will make an original contribution for applied technical knowledge in the identification, evaluation, and/or control of occupational safety and health hazards (e.g., development of a diagnostic technique for early detection of an occupational disease). A minimum of 60 percent time must be committed to research, although full-time is desirable. A for-profit organization will be required to submit a certification as to its status as part of the application. Awards are made to institutions in the name of individual applicants. EVALUATION CRITERIA Applications will be reviewed initially by a designated review group for scientific and technical merit. Particular attention will be given to the applicant's scientific achievements, career potential, the significance of the proposed research, scientific competence of the proposed principal investigator, and supporting faculty (where appropriate) in relationship to the type of research involved, feasibility of the project, likelihood of its producing meaningful results, appropriateness of the proposed budget, adequacy of available resources, and the supportive nature of the research environment. A secondary review will also be conducted for programmatic importance which will include: o Results of the initial review; o Assessment of a proposed study for its responsiveness to this solicitation and for its significance to occupational safety and health priorities: o Clearly linked to occupational safety and health; o Contributes to achievement of the research objectives specified in Section 20 (a) of the Occupational Safety and Health Act of 1970 and in Section 501 of the Federal Mine Safety and Health Amendments Act of 1977; o Makes original contribution for applied technical knowledge in the identification, evaluation, and/or control of occupational safety and health hazards; o Addresses a question(s) that when answered will provide knowledge upon which to take prevention action or to address another question(s) in a logical sequence of investigations toward preventing a health or safety problem. The logical sequence need not be defined rigidly, but there must be a likelihood of producing useful results. Judgment of the importance of the question(s) to be addressed is based on the magnitude of the problem, the severity of the effects, the extent of the application of the results, or the advance in knowledge to be derived by the project; o Program balance across areas of interest; and o Policy and budgetary considerations. METHOD OF APPLYING Applications should be submitted on the new form PHS 398 (Rev. 9/86) and must include the drug-free workplace certification. Application kits are available at most institutional business offices and from: Office of Grants Inquiries Division of Research Grants Westwood Building, Room 449 National Institutes of Health Bethesda, Maryland 20892 Applications will be accepted in accordance with special receipt dates for NIOSH SERCA applications--March 1, July 1, and November 1. It is essential that applicants type "NIOSH SERCA in Occupational Safety and Health" in item 2 on the face page of the application form. The original and six copies of the application should be submitted to the following address: Division of Research Grants National Institutes of Health Westwood Building, Room 240 Bethesda, Maryland 20892** Awards will be made based on priority score ranking and programmatic importance, as well as availability of funds. Vol. 18, No. 17, May 12, 1989 - Page 5 Questions concerning this SERCA grant program should be addressed: Ms. Barbara Beaullieu Grants Program Advisor Grants Program Office National Institute for Occupational Safety and Health Centers for Disease Control Building 1, Room 3053, MS-D30 Atlanta, Georgia 30333 Telephone: (404) 639-3343 A MORE COMPLETE DESCRIPTION AND GUIDELINES FOR APPLYING FOR A SERCA GRANT IN THE AREA OF OCCUPATIONAL SAFETY AND HEALTH MAY BE OBTAINED FROM THE NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH AT THE ABOVE ADDRESS. MINORITY INSTITUTIONS RESEARCH DEVELOPMENT PROGRAM P.T. 34, FF; K.W. 1002030, 0404000, 0710030, 0785035, 0730070 National Institute of Mental Health National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse The National Institute of Mental Health (NIMH), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), and the National Institute on Drug Abuse (NIDA) announce the Minority Institutions Research Development Program (MIRDP) which is designed to increase the capacity of predominantly minority institutions and their faculty research environment of minority institutions through the provision of grant support to develop and/or expand their existing capacity for this research and to enhance the research capability of their faculty to conduct neuroscience, behavioral, biological, clinical, public health, and social science research in alcohol, drug abuse, and mental health (ADM) areas. An applicant institution must be a public or private nonprofit university, 4-year college, or other institution with a traditionally high (more than 50 percent) minority student enrollment, an institution with a substantial enrollment of minority students which provides evidence of efforts to recruit into scientific careers members of ethnic or racial groups who have been found to be underrepresented in biomedical and behavioral research, or an Indian tribe which, in conjunction with one or more institutions of higher learning, offers undergraduate and graduate degrees in ADM disciplines. In fiscal year 1990, it is estimated that NIMH will provide approximately $1 million to support new awards under this announcement, NIAAA will provide approximately $200,000, and NIDA will provide approximately $200,000. For funding in fiscal year 1990, applications will be accepted under the single receipt date of November 15, 1989. Thereafter, applications in response to this announcement will be accepted on the usual Public Health Service receipt dates for new applications. Potential applicants are encouraged to contact the following staff for information and guidance: National Institute of Mental Health Marion E. Primas, Ph.D. Minority Research Resources Branch Division of Biometry and Applied Sciences, NIMH 5600 Fishers Lane, Room 18-101 Rockville, Maryland 20857 Telephone: (301) 443-3724 National Institute on Alcohol Abuse and Alcoholism Albert A. Pawlowski, Ph.D. Associate Director, Division of Basic Research, NIAAA 5600 Fishers Lane, Room 14C-20 Rockville, Maryland 20857 Telephone: (301) 443-1273 Vol. 18, No. 17, May 12, 1989 - Page 6 National Institute on Drug Abuse Catherine S. Bell-Bolek, M.S. Associate Director for Special Populations Research Office of the Director, NIDA 5600 Fishers Lane, Room 8A-54 Rockville, Maryland 20857 Telephone: (301) 443-0441 ENVIRONMENTAL HEALTH SCIENCES CORE CENTER GRANTS P.T. 34, 04; K.W. 0725005, 0710030, 0730070 National Institute of Environmental Health Sciences The National Institute of Environmental Health Sciences (NIEHS) uses a variety of award mechanisms to accomplish its mission of studying the mechanisms and effects of environmental agents on human health. Among these are Environmental Health Sciences Center Grants, a program of core center support (P30). The objective of this program is to provide core support for an administrative structure, scientific leadership, and shared core equipment to groups of productive scientists with programs in environmental health. The award allows these scientists to: (1) focus their research efforts on issues of relevance to the Institute, (2) work in an environment conducive to inter-disciplinary approaches to such research, and (3) serve as a resource to the NIEHS in providing scientific expertise on critical public health issues. Direct research support is NOT provided by the grant, except for limited funds for pilot projects or exploratory research. The Institute currently supports eleven such centers, and the funding of additional centers is subject to budget and other limitations. Because of these limitations and the special nature of the program, it is imperative that potential applicants contact NIEHS staff to discuss the scope, content, size, and timing of any applications for this program. Initial inquiries and requests for additional information should be directed to: Dr. Christopher O. Schonwalder Chief, Scientific Programs Branch Division of Extramural Research and Training National Institute of Environmental Health Sciences Research Triangle Park, North Carolina 27709 Telephone: (919) 541-7634 **THE MAILING ADDRESS GIVEN FOR SENDING APPLICATIONS TO THE DIVISION OF RESEARCH GRANTS OR CONTACTING PROGRAM STAFF IN THE WESTWOOD BUILDING IS THE CENTRAL MAILING ADDRESS FOR THE NATIONAL INSTITUTES OF HEALTH. APPLICANTS WHO USE EXPRESS MAIL OR A COURIER SERVICE ARE ADVISED TO FOLLOW THE CARRIER'S REQUIREMENTS FOR SHOWING A STREET ADDRESS. THE ADDRESS FOR THE WESTWOOD BUILDING IS: 5333 Westbard Avenue Bethesda, Maryland 20816 Vol. 18, No. 17, May 12, 1989 - Page 7