NOTICES NIH WORKSHOP - PROTECTION OF HUMAN SUBJECTS .............(84/138)............ 1 National Institutes of Health Index: NATIONAL INSTITUTES OF HEALTH INCLUSION OF MINORITIES IN STUDY POPULATIONS ............(141/328)........... 1 National Institutes of Health Alcohol, Drug Abuse, and Mental Health Administration Index: NATIONAL INSTITUTES OF HEALTH ALCOHOL, DRUG ABUSE, AND MENTAL HEALTH ADMINISTRATION INCLUSION OF WOMEN IN STUDY POPULATIONS .................(331/360)........... 4 National Institutes of Health Index: NATIONAL INSTITUTES OF HEALTH DATED ANNOUNCEMENTS (RFPs AND RFAs) MAINTENANCE AND SUPPLY OF SCHISTOSOME INFECTED SNAILS AND MAMMALS (RFP) ..... 4 National Institute of Allergy and Infectious Diseases (366/413) Index: ALLERGY AND INFECTIOUS DISEASES ONGOING PROGRAM ANNOUNCEMENTS RESEARCH ON REIMBURSEMENT ISSUES IN MENTAL HEALTH SERVICES DELIVERY ......... 5 National Institute of Mental Health (419/457) Index: MENTAL HEALTH ALZHEIMER'S DISEASE TREATMENT AND FAMILY STRESS ............................. 5 National Institute of Mental Health (460/494) Index: MENTAL HEALTH PLEASE NOTE: The NIH GUIDE FOR GRANTS AND CONTRACTS will not be published on June 23, 1989. The next issue of the GUIDE will be June 30, 1989. NOTICES NIH WORKSHOP - PROTECTION OF HUMAN SUBJECTS P.T. 42; K.W. 1014002, 0783005 National Institutes of Health The Office for Protection from Research Risks, National Institutes of Health, is sponsoring a workshop on ethical issues involved in behavioral and biomedical research. The two-day program will convene the morning of August 16 with a presentation on the Historic Overview of Ethics in Research. The workshop is open to anyone with an interest in research, as well as NIH personnel involved in the development of research protocols, the review of research proposals and applications, the awarding of NIH research funds, the performance of research, and the evaluation of research. Advanced registration is required. Dates: August 16-17, 1989 Location: Lister Hill Auditorium Building 38A National Institutes of Health 9000 Rockville Pike Bethesda, Maryland 20892 Title of Workshop: "Ethical Issues in Biomedical and Behavioral Research" Registration Contact: Ms. Darlene M. Ross Education Program Coordinator Office for Protection from Research Risks National Institutes of Health Building 31, Room 5B62 9000 Rockville Pike Bethesda, Maryland 20892 Telephone: (301) 496-8101 Program Contacts: Dr. Charles R. MacKay Director, Division of Program Development and Evaluation or Mr. Levi C. Carter Chief, Education Staff Division of Program Development and Evaluation National Institutes of Health Building 31, Room 5B62 9000 Rockville Pike Bethesda, Maryland 20892 Telephone: (301) 496-8101 INCLUSION OF MINORITIES IN STUDY POPULATIONS P.T. 34, FF; K.W. 1014002, 0710030 National Institutes of Health Alcohol, Drug Abuse, and Mental Health Administration The Secretary's Task Force on Black and Minority Health issued its report in October 1985. In its review of existing data, the Task Force noted the under representation of minorities in research studies. This has resulted in significant gaps in knowledge about minority subpopulations. This finding prompted the Task Force to recommend the expansion of biomedical and behavioral research to assure appropriate emphasis on health problems that disproportionately affect U.S. racial/ethnic minority populations (i.e., American Indian or Alaskan Natives, Asian/Pacific Islanders, Blacks, Hispanics). Currently, these problems include: cancer, chemical dependency, heart disease and stroke, homicide and accidents, diabetes, infant mortality and acquired immunodeficiency syndrome (AIDS). Vol. 18, No. 21, June 16, 1989 - Page 1 In these emphasis areas (noted above), there are clear scientific and public health reasons for specifically including members of minority groups in study populations. However, investigators should be aware that merely including an arbitrary number of minority group participants in a given study is insufficient to guarantee generalization of the results. In attempting to include minority groups in a particular study, attention must be paid to research design and sample size issues. Also, the NIH and ADAMHA urge applicants for grants and offerors for contracts to give added attention (where feasible and appropriate) to the inclusion of minorities in the study populations for research into the etiology of diseases, research in behavioral and social sciences, clinical studies of treatment and treatment outcomes, research on the dynamics of health care and its impact on disease, and appropriate interventions for disease prevention and health promotion. If minorities are not included in a given study, a clear rationale for their exclusion should be provided. For further clarification or discussion of these issues, contact the appropriate office listed below: NATIONAL INSTITUTE ON AGING Associate Director for Office of Extramural Affairs NIA, NIH Building 31, Room 5C02 Bethesda, Maryland 20892 Telephone: (301) 496-9322 NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES Director, Extramural Activities Program NIAID, NIH Westwood Building, Room 703 Bethesda, Maryland 20892 Telephone: (301) 496-7291 NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES Deputy Director, Extramural Activities Program NIAMS, NIH Westwood Building, Room 403C Bethesda, Maryland 20892 Telephone: (301) 496-7495 NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT Deputy Director NICHD, NIH Building 31, Room 2A03 Bethesda, Maryland 20892 Telephone: (301) 496-1848 NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS Acting Director, Extramural Activities NIDCD, NIH Federal Building, Room 1C11 Bethesda, Maryland 20892 Telephone: (301) 496-1804 NATIONAL INSTITUTE OF DENTAL RESEARCH Director, Extramural Program NIDR, NIH Westwood Building, Room 503 Bethesda, Maryland 20892 Telephone: (301) 496-7723 NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES Director, Division of Extramural Activities NIDDK, NIH Westwood Building, Room 657 Bethesda, Maryland 20892 Telephone: (301) 496-7277 Vol. 18, No. 21, June 16, 1989 - Page 2 NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES Director, Division of Extramural Research and Training NIEHS, NIH Building 3, Room 301A P.O. Box 12233 Research Triangle Park, North Carolina 27709 Telephone: (919) 629-7723 NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES Deputy Associate Director, Office of Program Activities NIGMS, NIH Westwood Building, Room 955 Bethesda, Maryland 20892 Telephone: (301) 496-7063 NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE Director, Division of Extramural Activities NINDS, NIH Federal Building, Room 1016A Bethesda, Maryland 20892 Telephone: (301) 496-9248 NATIONAL CANCER INSTITUTE Director, Division of Extramural Activities NCI, NIH Building 31, Room 10A03 Bethesda, Maryland 20892 Telephone: (301) 496-5147 NATIONAL EYE INSTITUTE Associate Director Extramural and Collaborative Program NEI, NIH Building 31, Room 6A51 Bethesda, Maryland 20892 Telephone: (301) 496-5983 NATIONAL HEART, LUNG AND BLOOD INSTITUTE Director, Division of Extramural Affairs NHLBI, NIH Westwood Building, Room 7A17B Bethesda, Maryland 20892 Telephone: (301) 496-7416 NATIONAL CENTER FOR NURSING RESEARCH Director, Extramural Programs NCNR, NIH Building 31, Room 5B09 Bethesda, Maryland 20892 Telephone: (301) 496-0523 NATIONAL LIBRARY OF MEDICINE Acting Associate Director, Division of Extramural Programs NLM, NIH Building 38A, 5N505 Bethesda, Maryland 20892 Telephone: (301) 496-4621 DIVISION OF RESEARCH RESOURCES Deputy Director, DRR, NIH Westwood Building, Room 8A16 Bethesda, Maryland 20892 Telephone: (301) 496-6023 Vol. 18, No. 21, June 16, 1989 - Page 3 ALCOHOL, DRUG ABUSE, AND MENTAL HEALTH ADMINISTRATION Associate Administrator for Extramural Programs ADAMHA Parklawn Building, Room 13-103 5600 Fishers Lane Rockville, Maryland 20857 Telephone: (301) 443-4266 INCLUSION OF WOMEN IN STUDY POPULATIONS P.T. 34, II; K.W. 0770000, 1014002 National Institutes of Health The Public Health Service Task Force on Women's Health Issues published its repo in the January 1985 issue of Public Health Reports. One of the Task Force's maj recommendations was that biomedical and behavioral research be expanded to assur appropriate emphasis on conditions and diseases unique to, or more prevalent in, women of all age groups. In keeping with one aspect of this recommendation, the NIH urges applicants for grants and offerors for contracts to consider the inclusion of women in the stud populations for all clinical research efforts. Exceptions would be studies of diseases which exclusively affect males or where involvement of pregnant women m expose the fetus to undue risks. Gender differences should be noted and evaluat If women are not to be included, a clear rationale should be provided for their exclusion. In order to provide more precise information to the medical community, it is recommended that publications resulting from NIH-supported research in which the study population was limited to one sex for any reason other than that the disea or condition studied exclusively affects that sex, should state, in the abstract summary, the gender of the population studied, e.g., "male patients," "male volunteers," "female patients," "female volunteers." For further clarification or discussion of these issues, contact those offices listed in the announcement above "INCLUSION OF MINORITIES IN STUDY POPULATIONS." DATED ANNOUNCEMENTS (RFPs AND RFAs) MAINTENANCE AND SUPPLY OF SCHISTOSOME INFECTED SNAILS AND MAMMALS RFP AVAILABLE: NIH-NIAID-MIDP-90-16 P.T. 34; K.W. 1002002, 1002032 National Institute of Allergy and Infectious Diseases The Parasitology and Tropical Diseases Branch of the Microbiology and Infectious Diseases Program of the National Institute of Allergy and Infectious Diseases (NIAID) is soliciting contract proposals from organizations having the capabilities and facilities to maintain all of the life-cycles of Schistosoma mansoni, Schistosoma hematobium and Schistosoma japonicum and to distribute the infected or uninfected vectors to qualified investigators. One contract may be awarded as a result of this solicitation. It is expected that the contract will have a five-year period of performance. Any responsible offeror may submit a proposal, which shall be considered by the Government. RFP-NIH-NIAID-MIDP-90-16 will be issued on June 23, 1989. Proposals will be due by close of business on August 22, 1989. Vol. 18, No. 21, June 16, 1989 - Page 4 To receive a copy of the RFP, please send a written request and two self-addressed mailing labels to: Ms. Joyce U. Sagami Contract Management Branch National Institute of Allergy and Infectious Diseases National Institutes of Health Westwood Building/Room 707 5333 Westbard Avenue Bethesda, Maryland 20892 This advertisement does not commit the Government to make an award. ONGOING PROGRAM ANNOUNCEMENTS RESEARCH ON REIMBURSEMENT ISSUES IN MENTAL HEALTH SERVICES DELIVERY P.T. 34; K.W. 0730050, 0715129, 0408006 National Institute of Mental Health The National Institute of Mental Health (NIMH) has revised its announcement on Research on Reimbursement Issues in Mental Health Services Delivery. The purpose of this revised announcement is to encourage investigator-initiated research on mental health services reimbursement issues, policies, and programs in order to promote the growth of scientific knowledge in mental health economics and assist in the development of improved reimbursement strategies. The revised announcement places increased emphasis on studies of innovative methods of reimbursement, such as capitation systems for severely mentally ill persons. It also encourages more research on effects of annual and lifetime limits on third-party reimbursement for mental health services and studies of financial burdens on patients and families resulting from lack of insurance or under-insurance for mental health care. Support under this announcement may be requested through applications for a regular research grant, Small Grant, First Independent Research Support and Transition (FIRST) Award, Scientist Development Award, Scientist Development Award for Clinicians, and Research Scientist Development Award (Level II). Applicants may request support for up to 5 years (with the exception of small grants, which are limited to 2 years). Applications will be reviewed according to the usual Public Health Service receipt and review schedule. Applicants seeking further information should contact the following: Paul Widem, Chief, or Agnes Rupp, Ph.D. Mental Health Economics Research Program Biometric and Clinical Applications Branch Division of Biometry and Applied Sciences National Institute of Mental Health 5600 Fishers Lane, Room 18C-14 Rockville, Maryland 20857 Telephone: (301) 443-4233 ALZHEIMER'S DISEASE TREATMENT AND FAMILY STRESS P.T. 34; K.W. 0715180, 0730010, 0715195, 0745070, 0755000 National Institute of Mental Health The National Institute of Mental Health (NIMH) has revised its announcement on Alzheimer's Disease Treatment and Family Stress (formerly Research on Family Stress and the Care of Alzheimer's Disease Victims, MH-86-07). Under this revised announcement, NIMH seeks applications for research that will increase knowledge and improve research methodology on family stress related to the care of individuals with Alzheimer's disease, and the development of family care and service delivery models. In addition to the traditional research project grant, other mechanisms of support that are available include the First Independent Research Support and Transition (FIRST) Award, Small Grant, Scientist Development Award, Scientist Development Award for Clinicians, Research Scientist Development Award (Levels II and V), and National Research Service Awards. Applicants may request Vol. 18, No. 21, June 16, 1989 - Page 5 support for up to 5 years (with the exception of small grants, which are limited to 2 years). Applications will be reviewed according to the usual Public Health Service receipt and review schedule. For further information, potential applicants should contact: Enid Light, Ph.D. Head, Alzheimer's Disease and Family Stress Program Mental Disorders of the Aging Research Branch Division of Clinical Research National Institute of Mental Health 5600 Fishers Lane, Room 11C-03 Rockville, Maryland 20857 Telephone: (301) 443-1185 Vol. 18, No. 21, June 16, 1989 - Page 6