The RCSB.org server holds more than 150000 PDB files but there are only a few thousand
different types of protein folds. So it is curious to see a few simplest.
Based on
Tertiary Protein Structure and Folds
and Protein Folds.
The Lone Helix: 1GCN - glucagon, a hormone involved in
regulating sugar metabolism in mammals (as does insulin).
See also glucagon-like peptide 2 - 2L63.
PDB
vdW
B&L
rib
HET
1Å=
HF
AA
FPS
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The Helix-turn-helix motif: 1ROP - RNA-binding protein Rop (a part of dimer really),
which is found in certain plasmids (small circular molecules of
double-stranded DNA occurring in bacteria and yeast) and involved in their replication.
The Four-helix Bundle: In four-helix-bundle proteins the interfaces between the helices consist mostly of
hydrophobic residues while polar side chains on the exposed surfaces interact with
the aqueous environment.
The ligand-binding sites of these proteins occur between the alpha helices.
1CCD - Clara cell protein.
2IJK - ColE1 Rom protein dimer.
1A7E - Myohemerythrin.
1FHA - Ferritin.
4ZF7 - Interleukin-2.
1HUW - human growth factor.
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